Company to Host Live Audio Webcast of MatrixOne Analyst Day 2003

WESTFORD, Mass.--(BUSINESS WIRE)--May 22, 2003-- MatrixOne, Inc. (NASDAQ: MONE), a leading provider of collaborative product lifecycle management (PLM) solutions for the value chain(TM), will host MatrixOne Analyst Day 2003 on Thursday, May 22, 2003 from 1:00 p.m. to 5:00 p.m. eastern time at the NASDAQ MarketSite in New York City. The audio portion of the event will be Webcast live to provide access to all interested parties. The audio portion of the event will also be available via Webcast replay for fourteen days following the event. The live Webcast and replay will be accessible from the Company's website at www.matrixone.com/investor.

About MatrixOne

MatrixOne, Inc. (NASDAQ: MONE) is a recognized leader in delivering collaborative product lifecycle management (PLM) solutions. We provide flexible solutions that unleash the creative power of global value chains to inspire innovations and speed them to market. MatrixOne's customers include global leaders in the aerospace and defense, automotive, consumer products, high technology, life sciences, machinery, and the process industries, including Agilent Technologies, General Electric, Honda, Johnson Controls, Philips, Procter & Gamble, Siemens, and Toshiba. MatrixOne ( http://www.matrixone.com/) is headquartered in Westford, Massachusetts, with locations throughout North America, Europe, and Asia/Pacific.

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MatrixOne and eMatrix are registered trademarks, and a leading provider of collaborative product lifecycle management (PLM) solutions for the value chain is a trademark of MatrixOne, Inc. All other trademarks and service marks are the property of their respective owners.

Forward-looking statements in this release are subject to risks and uncertainties that could cause our actual results to differ materially from those anticipated. Such statements may relate, among other things, to our plans, objectives and expected financial and operating results. The risks and uncertainties that may affect forward-looking statements include, among others: poor product sales, long sales cycles, difficulty developing new products, difficulty in relationships with vendors and partners, higher risk in international operations, difficulty assimilating future acquisitions, difficulty managing rapid growth, and increased competition. For more about the risks and uncertainties of our business, see our periodic and other S.E.C. filings.

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             Brian Norris, 978/589-4040                             
             
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